Searchable abstracts of presentations at key conferences in endocrinology

ea0056oc9.3 | Thyroid from basics to clinics | ECE2018

A mouse model of BRAF V600E mutated papillary thyroid cancer imitating sporadic conditions

Jakubikova Iva , Schoultz Elin , Johansson Ellen , Liang Shawn , Patyra Konrad , Kero Jukka , Zak Pavel , Nilsson Mikael

Introduction: Worldwide constantly rising incidence of thyroid cancer promotes research activities. Nowadays the most speculated issue is the clinical significance of BRAF mutation. For sure BRAF mutation is a cancer-specific somatic mutation consistent with papillary thyroid cancer phenotype, otherwise, its role in tumor aggressiveness, progression, and the overall poor outcome is controversial. As far as several clinical studies claim opposing opinions, the learning aspect o...